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It is important to highlight that not all anti-diabetic drugs appear suitable for repositioning given their potential pro-tumorigenic effects.The effects of anti-diabetica drugs in thyroid cancer are summarized in Figure 1
Couto N, Wood J, Barber J
It does not predict response to MIC-B12 or any compound
Compared with WT SOD1, disease-linked mutant SOD1 proteins readily form monomers by reduction of the disulfide bond between Cys-57 and Cys-146 or by demetallation at the dimer interface (Tiwari and Hayward, 2003
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